PLLA is a biodegradable material. In the natural environment or in the body, it gradually degrades into L-lactic acid through ester bond hydrolysis and is eventually metabolized into carbon dioxide and water. It is environmentally friendly and in line with the concept of sustainable development.
Under normal conditions, PLLA has good tolerance to most organic solvents and chemical reagents. However, in strong acid, strong base, or high temperature and high humidity environments, the degradation rate will be accelerated and the chemical structure may be destroyed.
Due to the chirality of its monomer, L-lactide, PLLA also possesses chirality. This chirality allows it to exhibit specificity when interacting with other chiral molecules, leading to unique applications in drug delivery and biosensors.
PLLA-based sutures offer excellent biocompatibility and mechanical properties. They provide sufficient strength during initial wound healing and gradually degrade and absorb, eliminating the need for suture removal and reducing patient pain and infection risk. They are commonly used in surgical procedures to suture skin, muscle, and internal organs.
PLLA can be formulated into microspheres, nanoparticles, or implants as drug carriers. By controlling the degradation rate of PLLA, slow and sustained drug release is achieved, improving efficacy and minimizing toxic side effects. It holds broad application prospects in cancer treatment and vaccine delivery.
PLLA has a suitable pore structure and surface properties, which can provide a good environment for cell adhesion, proliferation and differentiation. It can be used as a scaffold material to repair and regenerate damaged tissues and organs, such as bone, cartilage, and nerve tissue.
Its excellent transparency, barrier properties, and biodegradability make it suitable for food packaging. It effectively blocks oxygen, moisture, and odors, extending the shelf life of food. It also naturally degrades after use, reducing environmental pollution. It is commonly used for packaging fruits, vegetables, meat, and dairy products.
It is also used in packaging daily necessities such as cosmetics, detergents, and electronics. Its aesthetic appearance and environmentally friendly properties enhance product quality and market competitiveness.
PLLA can be made into fibers for textiles. These fibers offer a soft feel, excellent moisture absorption and breathability, and are naturally UV-resistant. They can be used in clothing, home textiles, nonwovens, and other products, and have potential for growth in the high-end textile market.
| 33135-50-1 | Project Name | Method | Limit |
|---|---|---|---|
Poly(L-lactide)、 Poly(L-lacticacid） | Traits | visual | White to yellow solid |
| Moisture | Karl Fischer-Coulomb method | ＜0.5% | |
| Monomer residue | Gas chromatography | L-LA≤0.5% | |
| Tin content | ICP-OES | ≤150ppm |
| 33135-50-1 | Project Name | Method | Limit |
|---|---|---|---|
Poly(L-lactide)、 Poly(L-lacticacid） | Heavy metals (expressed as Pb) | ICP-OES | ≤10ppm |
| Solvent residues | Gas chromatography | Acetone≤0.1% Toluene≤890ppm | |
| Intrinsic viscosity | Capillary viscometer | 1.0-5.0dL/g (HFIP25℃,C=0.1g/dL) | |
| Burnt residue | High temperature burning | ≤0.2% |
